Not directly related to MakeHuman, but here goes:
The fact that you say "Wine" makes me assume you use some form of Linux as operating system.
The fact that it opens Wine "automatically" makes me assume that you have clicked on a .exe file (which filetype is probably associated with wine).
The solution is to download
Blender for linux, not blender for windows.
Go to
http://www.blender.org/download/#linux and click "
GNU/Linux" (it should look green), then download a 32 or 64 bit package.