Joint helpers in maketarget

I understand that the joint helpers need to be moved to stay consistent with any changes you make in your custom targets. But what happens if the join helpers themselves are changed? If you scale them, or let them be grabbed by proportional edits, they will be slightly squished or stretched. Does this matter?
How exactly is the helper geo even detected and used? Vertex index?
Are the eye, eyelash and teeth geometries that come when you load the base mesh from maketarget in blender essential to maintaining vertex count?
How exactly is the helper geo even detected and used? Vertex index?
Are the eye, eyelash and teeth geometries that come when you load the base mesh from maketarget in blender essential to maintaining vertex count?