Yes.
Contrary to popular opinion, it is perfectly possible to make extreme characters that will work fine with both morphs and posing
The steps I took to produce this was:
* Load a human mesh via maketarget
* Load the target asian-female-young.target (via button in maketarget)
* Load the target female-young-averagemuscle-averageweight-maxcup-averagefirmness.target (via button in maketarget)
* Create "new secondary target"
* Model the body to my liking (without horns, see further down)
* Move joint cubes so they are inside the actual joints
* Create a target ("extreme2", seen in screenshots)
* Duplicate the mesh
* Assign duplicate mesh the type "clothing" (in makeclothes)
* Delete joint cubes
* Delete Eyelashes and eyeballs
* Extrude horns
* autocreate vertex groups (to the entire clothes mesh)
* Remove horn vertices from "left" and "right" vertex groups
* Create new groups *lefthorn and *righthorn (note asterisk) on both human and clothes
* Assign the horns to *lefthorn and *righthorn on clothes
* Select three vertices on the bottom of the horn and assign to either *..horn on the human
* MakeClothes
* Rename/move generatet clothes to have them in the proxymeshes folder
I now have one proxy and one target which in combination produces the desired result.