A quick search didn't turn up anything so I thought I would ask.
Have you thought about making a portable version of Makehuman like the one available for Blender, see http://portableapps.com/apps/graphics_pictures/blender_portable their contact info at: http://portableapps.com/about/contact.
You are almost there now since your program doesn't have to go to a specific directory. The only problem is there seems to be no way around placement of library of files in the default Windows user directories.
I installed and run Makehuman in PortableApps directory structure and it seems to run OK. I just have to keep telling it where to put my files all the time. When my hard drive crashed, I just took my jumpdrive to my laptop and worked there.
I don't know how hard it would be to let the user select where to store Makehuman's libraries and keep that information in ini files. That seems to be what makes it easier to make PortableApps instead of changing the registry.
PortableApps is open source. It works with: Windows 2000, Windows XP, Windows Vista, Windows 7, Windows 8 & Windows 8.1and Linux, Unix, BSD, etc via Wine & Mac OS X via CrossOver, Wineskin, WineBottler, PlayOnMac
I know you're facing a 'deadline' on your next release. Just wondered if you were aware of or interested in the possibility.
Thanks,
Wil