So I downloaded a blender test build and played around with the new principled shader. Kind of nifty. Very useful. The significant objective gain you can get over most other prior node setups, is that it does away with the very annoying fresnel artifacts you get when the camera ray angle approaches 90 degrees vs a surface normal (this is especially visible when using normal maps).
But outside that, it very conveniently merges pretty much everything one would want into one node.
Here's a test render with principled skin (left) vs classic diffuse/glossy/fresnel (right). It's not entirely fair since I also enabled some sss in the principled:
Node setup for principled:
Node setup for old-style: